Immune / Recovery

LL-37

Price Range

$7.80 – $17.80/mg

Vendors

10

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6

Immune SupportRecovery

Where to Buy

Compare LL-37 prices across verified vendors. Affiliate links support Pushing Peptides.

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Price/mg

$7.80

Vial

10mg

Price

$78.00

Price/mg

$11.80

Vial

5mg

Price

$59.00

Price/mg

$13.14

Vial

5mg

Price

$65.70

Price/mg

$17.80

Vial

5mg

Price

$89.00

Price/mg

Vial

Price

$59.99

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Overview

LL-37 is the only human cathelicidin antimicrobial peptide, a 37-amino acid peptide cleaved from the C-terminus of the precursor protein hCAP18. It is expressed by neutrophils, macrophages, and epithelial cells as a first-line innate immune defense molecule with broad-spectrum antimicrobial and immunomodulatory activity.

Mechanism of Action

LL-37 disrupts microbial membranes through electrostatic interactions with negatively charged lipid bilayers, creating pores that kill bacteria, fungi, and enveloped viruses. Beyond direct antimicrobial action, it modulates immune cell recruitment (chemotaxis), promotes wound healing and angiogenesis, neutralizes endotoxin (LPS), and influences adaptive immune responses through dendritic cell modulation.

Research Context

LL-37 research spans infectious disease, wound healing, autoimmune conditions, and cancer immunology. Its dual role as both antimicrobial agent and immune modulator makes it unique among research peptides.

Key Research Areas

Broad-spectrum antimicrobial mechanisms
Biofilm disruption and antibiotic resistance research
Wound healing and re-epithelialization
LPS neutralization and sepsis models
Cancer immunology (both pro- and anti-tumorigenic effects)
Innate-adaptive immune bridging

Considerations for Researchers

Larger peptide (37 amino acids) with amphipathic structure. Store lyophilized at -20C. The antimicrobial nature means contamination testing is especially important. Reconstitute with endotoxin-free water for immunology research.

Disclaimer: All information on this page is for research purposes only and is not intended as medical advice. Peptide research should be conducted by qualified professionals in appropriate laboratory settings. Pushing Peptides does not sell peptides. We aggregate publicly available pricing and vendor data.