Weight Loss

GLP3-R + GLP2-T Blend

Price Range

Price varies

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Weight LossAppetite ControlMetabolic Support

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Overview

This blend combines Retatrutide (GLP3-R) and Tirzepatide (GLP2-T) in a single formulation. The combination pairs a triple-agonist (GIP/GLP-1/glucagon) with a dual-agonist (GLP-1/GIP), theoretically adding glucagon receptor activation on top of enhanced GLP-1/GIP signaling.

Mechanism of Action

Retatrutide contributes GIP, GLP-1, and glucagon receptor activation. Tirzepatide adds additional GLP-1 and GIP receptor engagement. The net effect amplifies GLP-1 and GIP pathway activity while adding the unique glucagon-mediated thermogenesis and hepatic fat oxidation from the retatrutide component.

Key Research Areas

Multi-peptide metabolic receptor saturation studies
Glucagon receptor additive effects in dual-agonist contexts
Dose-optimization for multi-component weight loss protocols

Considerations for Researchers

Very limited vendor base (4 vendors). Novel combination without established research protocols. Verify exact component ratios. Store at -20C.

Disclaimer: All information on this page is for research purposes only and is not intended as medical advice. Peptide research should be conducted by qualified professionals in appropriate laboratory settings. Pushing Peptides does not sell peptides. We aggregate publicly available pricing and vendor data.