Humanin
Price Range
$11.99 – $14.70/mg
Vendors
4
Views
4
Where to Buy
Compare Humanin prices across verified vendors. Affiliate links support Pushing Peptides.
| Vendor | Price/mg | Vial Size | Price/Vial | |
|---|---|---|---|---|
| $11.99 | 10mg | $119.90 | ||
| $14.70 | 10mg | $147.00 | ||
| — | — | — | ||
| — | — | — |
Price/mg
$11.99
Vial
10mg
Price
$119.90
Price/mg
$14.70
Vial
10mg
Price
$147.00
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Overview
Humanin is a 24-amino acid mitochondria-derived peptide (MDP) encoded by the 16S rRNA gene of mitochondrial DNA. Discovered in 2001 in surviving neurons of Alzheimer's disease patients, it was the first identified MDP and has since been recognized as a key player in cellular stress resistance, metabolic regulation, and aging.
Mechanism of Action
Humanin activates the STAT3 signaling pathway via a trimeric receptor complex (CNTFR/WSX-1/gp130). It also binds to IGFBP-3, competing with IGF-1 for binding and modulating IGF-1 bioavailability. Intracellularly, it interacts with BAX to prevent apoptosis and protects mitochondrial membrane integrity under stress conditions.
Research Context
Humanin levels decline with age and are inversely correlated with age-related disease risk. Research has explored its roles in Alzheimer's disease neuroprotection, cardiovascular protection, metabolic regulation, and as a potential longevity biomarker.
Key Research Areas
Considerations for Researchers
Extremely limited vendor availability (1 vendor). Premium pricing for the larger MDP. Store at -20C. Research-grade material may be difficult to source.
Disclaimer: All information on this page is for research purposes only and is not intended as medical advice. Peptide research should be conducted by qualified professionals in appropriate laboratory settings. Pushing Peptides does not sell peptides. We aggregate publicly available pricing and vendor data.