ARA-290
Price Range
$4.80 – $6.00/mg
Vendors
15
Views
4
Where to Buy
Compare ARA-290 prices across verified vendors. Affiliate links support Pushing Peptides.
| Vendor | Price/mg | Vial Size | Price/Vial | |
|---|---|---|---|---|
| $4.80 | 10mg | $48.00 | ||
| $6.00 | 10mg | $60.00 | ||
Instant PeptidesVerified | $6.00 | 10mg | $60.00 | View |
| $5.00 | 30mg | $149.99 | ||
| $5.31 | 16mg | $85.00 |
Price/mg
$4.80
Vial
10mg
Price
$48.00
Price/mg
$6.00
Vial
10mg
Price
$60.00
Price/mg
$5.00
Vial
30mg
Price
$149.99
Price/mg
$5.31
Vial
16mg
Price
$85.00
Overview
ARA-290 (Cibinetide) is a synthetic 11-amino acid peptide derived from the three-dimensional structure of erythropoietin (EPO). It selectively activates the innate repair receptor (IRR), a heterocomplex of EPO receptor and beta common receptor (CD131), without stimulating erythropoiesis (red blood cell production). This separates the tissue-protective effects of EPO from its blood-thickening effects.
Mechanism of Action
ARA-290 binds to the innate repair receptor, triggering anti-inflammatory and tissue-protective signaling cascades. This includes suppression of pro-inflammatory cytokine production, promotion of anti-inflammatory macrophage polarization (M1 to M2 shift), and support of nerve fiber regeneration. Unlike EPO, it does not activate the classical EPO receptor homodimer, so it does not stimulate erythropoiesis.
Research Context
Clinical studies have explored ARA-290 in small fiber neuropathy, sarcoidosis, type 2 diabetes with neuropathic pain, and chronic inflammatory conditions. Its ability to promote nerve fiber regeneration is of particular interest.
Key Research Areas
Considerations for Researchers
Moderately available from 27 vendors. Store lyophilized at -20C. The selective receptor targeting makes purity verification important to confirm the absence of EPO contamination.
Disclaimer: All information on this page is for research purposes only and is not intended as medical advice. Peptide research should be conducted by qualified professionals in appropriate laboratory settings. Pushing Peptides does not sell peptides. We aggregate publicly available pricing and vendor data.